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	<id>https://wiki.cakele.iodatalabs.dev/index.php?action=history&amp;feed=atom&amp;title=DGI%3ALymeborreliose%2FTherapie</id>
	<title>DGI:Lymeborreliose/Therapie - Revision history</title>
	<link rel="self" type="application/atom+xml" href="https://wiki.cakele.iodatalabs.dev/index.php?action=history&amp;feed=atom&amp;title=DGI%3ALymeborreliose%2FTherapie"/>
	<link rel="alternate" type="text/html" href="https://wiki.cakele.iodatalabs.dev/index.php?title=DGI:Lymeborreliose/Therapie&amp;action=history"/>
	<updated>2026-06-11T03:45:51Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wiki.cakele.iodatalabs.dev/index.php?title=DGI:Lymeborreliose/Therapie&amp;diff=1140&amp;oldid=prev</id>
		<title>imported&gt;Maximilian.schons@uk-koeln.de: Textersetzung - „die Patienten“ durch „die Patient:innen“</title>
		<link rel="alternate" type="text/html" href="https://wiki.cakele.iodatalabs.dev/index.php?title=DGI:Lymeborreliose/Therapie&amp;diff=1140&amp;oldid=prev"/>
		<updated>2021-06-15T09:10:23Z</updated>

		<summary type="html">&lt;p&gt;Textersetzung - „die Patienten“ durch „die Patient:innen“&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;col class=&quot;diff-content&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 09:10, 15 June 2021&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l93&quot;&gt;Line 93:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 93:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;====Post-Treatment-Lyme-Disease-Syndrome====&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;====Post-Treatment-Lyme-Disease-Syndrome====&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;&amp;gt;Bei fehlendem Nachweis einer (Re-)Infektion oder fehlender Kenntnis eines Therapieversagens soll keine weitere antibiotische Therapie angestrebt werden. Studien geben nicht nur keinen Hinweis auf einen Benefit hinsichtlich des outcomes für die &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Patienten&lt;/del&gt;, sondern sogar nachteilige Effekt [6], die in einer negativen Nutzen-Risiko-Bewertung für die antibiotische Therapie münden. Von einer antibiotischen Therapie wird daher abgeraten.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;&amp;gt;Bei fehlendem Nachweis einer (Re-)Infektion oder fehlender Kenntnis eines Therapieversagens soll keine weitere antibiotische Therapie angestrebt werden. Studien geben nicht nur keinen Hinweis auf einen Benefit hinsichtlich des outcomes für die &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Patient:innen&lt;/ins&gt;, sondern sogar nachteilige Effekt [6], die in einer negativen Nutzen-Risiko-Bewertung für die antibiotische Therapie münden. Von einer antibiotischen Therapie wird daher abgeraten.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Eine Therapie der PTLDS sollte nach symptomorientierten Gesichtspunkten erfolgen und eine Differentialdiagnostik angestrebt werden.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Eine Therapie der PTLDS sollte nach symptomorientierten Gesichtspunkten erfolgen und eine Differentialdiagnostik angestrebt werden.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;br /&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;br /&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;

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&lt;/table&gt;</summary>
		<author><name>imported&gt;Maximilian.schons@uk-koeln.de</name></author>
	</entry>
	<entry>
		<id>https://wiki.cakele.iodatalabs.dev/index.php?title=DGI:Lymeborreliose/Therapie&amp;diff=1139&amp;oldid=prev</id>
		<title>imported&gt;Bestem at 12:40, 15 December 2020</title>
		<link rel="alternate" type="text/html" href="https://wiki.cakele.iodatalabs.dev/index.php?title=DGI:Lymeborreliose/Therapie&amp;diff=1139&amp;oldid=prev"/>
		<updated>2020-12-15T12:40:28Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 12:40, 15 December 2020&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l6&quot;&gt;Line 6:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 6:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Mittel der Wahl sind Doxycyclin oder Amoxicillin für 30 Tage. Falls mehrere Wochen nach initialer antibiotischer Therapie noch Beschwerden berichtet werden, kann ein weiterer Therapieversuch mit Ceftriaxon oder Cefotaxim für 14-21 Tage angedacht werden. Von der Durchführung weiterer Therapiezyklen, einer Langzeittherapie, einer Pulstherapie, dem Einsatz alternativer Antibiotika oder von Kombinationstherapie wird abgeraten.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Mittel der Wahl sind Doxycyclin oder Amoxicillin für 30 Tage. Falls mehrere Wochen nach initialer antibiotischer Therapie noch Beschwerden berichtet werden, kann ein weiterer Therapieversuch mit Ceftriaxon oder Cefotaxim für 14-21 Tage angedacht werden. Von der Durchführung weiterer Therapiezyklen, einer Langzeittherapie, einer Pulstherapie, dem Einsatz alternativer Antibiotika oder von Kombinationstherapie wird abgeraten.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{| class=&quot;wikitable sortable &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;filterable &lt;/del&gt;MsoTableGrid&quot; border=&quot;1&quot; cellspacing=&quot;0&quot; cellpadding=&quot;0&quot; width=&quot;628&quot; style=&quot;box-sizing: inherit; border-collapse: collapse; border-spacing: 0px; background-color: rgb(255, 255, 255); font-size: 14px; font-family: &amp;amp;quot;Open Sans&amp;amp;quot;, Roboto, arial, sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: 2; text-align: start; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: 0px; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); text-size-adjust: auto; margin-left: -0.25pt; border: none;&quot;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{| class=&quot;wikitable sortable &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;bs-exportable &lt;/ins&gt;MsoTableGrid&quot; border=&quot;1&quot; cellspacing=&quot;0&quot; cellpadding=&quot;0&quot; width=&quot;628&quot; style=&quot;box-sizing: inherit; border-collapse: collapse; border-spacing: 0px; background-color: rgb(255, 255, 255); font-size: 14px; font-family: &amp;amp;quot;Open Sans&amp;amp;quot;, Roboto, arial, sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: 2; text-align: start; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: 0px; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); text-size-adjust: auto; margin-left: -0.25pt; border: none;&quot;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| style=&amp;quot;background-color:rgb(191, 191, 191);border-left-style:init;border-right-style:init;border-top-style:init;border-bottom-style:init;width:80.85pt;&amp;quot; width=&amp;quot;108&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;Klinische Situation&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| style=&amp;quot;background-color:rgb(191, 191, 191);border-left-style:init;border-right-style:init;border-top-style:init;border-bottom-style:init;width:80.85pt;&amp;quot; width=&amp;quot;108&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;Klinische Situation&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;border-left-style:init;border-right-style:solid;border-top-style:solid;border-bottom-style:solid;width:66.55pt;&amp;quot; width=&amp;quot;89&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Präferenz&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;border-left-style:init;border-right-style:solid;border-top-style:solid;border-bottom-style:solid;width:66.55pt;&amp;quot; width=&amp;quot;89&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Präferenz&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l52&quot;&gt;Line 52:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 52:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Anders als bei der kutanen Borreliose kommt Azithromycin aufgrund der Möglichkeit der QT-Zeit Verlängerung, nicht als Therapiealternative in Frage.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Anders als bei der kutanen Borreliose kommt Azithromycin aufgrund der Möglichkeit der QT-Zeit Verlängerung, nicht als Therapiealternative in Frage.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{| class=&quot;wikitable sortable &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;filterable &lt;/del&gt;MsoTableGrid&quot; border=&quot;1&quot; cellspacing=&quot;0&quot; cellpadding=&quot;0&quot; width=&quot;616&quot; style=&quot;box-sizing: inherit; border-collapse: collapse; border-spacing: 0px; background-color: rgb(255, 255, 255); font-size: 14px; font-family: &amp;amp;quot;Open Sans&amp;amp;quot;, Roboto, arial, sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: 2; text-align: start; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: 0px; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); text-size-adjust: auto; margin-left: -0.25pt; border: none;&quot;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{| class=&quot;wikitable sortable &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;bs-exportable &lt;/ins&gt;MsoTableGrid&quot; border=&quot;1&quot; cellspacing=&quot;0&quot; cellpadding=&quot;0&quot; width=&quot;616&quot; style=&quot;box-sizing: inherit; border-collapse: collapse; border-spacing: 0px; background-color: rgb(255, 255, 255); font-size: 14px; font-family: &amp;amp;quot;Open Sans&amp;amp;quot;, Roboto, arial, sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: 2; text-align: start; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: 0px; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); text-size-adjust: auto; margin-left: -0.25pt; border: none;&quot;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| style=&amp;quot;background-color:rgb(191, 191, 191);width:78.6pt;&amp;quot; width=&amp;quot;105&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;Klinische Situation&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| style=&amp;quot;background-color:rgb(191, 191, 191);width:78.6pt;&amp;quot; width=&amp;quot;105&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;Klinische Situation&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;width:66.5pt;&amp;quot; width=&amp;quot;89&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Präferenz&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;width:66.5pt;&amp;quot; width=&amp;quot;89&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Präferenz&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;

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&lt;/table&gt;</summary>
		<author><name>imported&gt;Bestem</name></author>
	</entry>
	<entry>
		<id>https://wiki.cakele.iodatalabs.dev/index.php?title=DGI:Lymeborreliose/Therapie&amp;diff=1138&amp;oldid=prev</id>
		<title>imported&gt;Bestem at 12:39, 15 December 2020</title>
		<link rel="alternate" type="text/html" href="https://wiki.cakele.iodatalabs.dev/index.php?title=DGI:Lymeborreliose/Therapie&amp;diff=1138&amp;oldid=prev"/>
		<updated>2020-12-15T12:39:48Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;a href=&quot;https://wiki.cakele.iodatalabs.dev/index.php?title=DGI:Lymeborreliose/Therapie&amp;amp;diff=1138&amp;amp;oldid=1137&quot;&gt;Show changes&lt;/a&gt;</summary>
		<author><name>imported&gt;Bestem</name></author>
	</entry>
	<entry>
		<id>https://wiki.cakele.iodatalabs.dev/index.php?title=DGI:Lymeborreliose/Therapie&amp;diff=1137&amp;oldid=prev</id>
		<title>imported&gt;Bestem at 12:38, 15 December 2020</title>
		<link rel="alternate" type="text/html" href="https://wiki.cakele.iodatalabs.dev/index.php?title=DGI:Lymeborreliose/Therapie&amp;diff=1137&amp;oldid=prev"/>
		<updated>2020-12-15T12:38:40Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 12:38, 15 December 2020&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l6&quot;&gt;Line 6:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 6:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Mittel der Wahl sind Doxycyclin oder Amoxicillin für 30 Tage. Falls mehrere Wochen nach initialer antibiotischer Therapie noch Beschwerden berichtet werden, kann ein weiterer Therapieversuch mit Ceftriaxon oder Cefotaxim für 14-21 Tage angedacht werden. Von der Durchführung weiterer Therapiezyklen, einer Langzeittherapie, einer Pulstherapie, dem Einsatz alternativer Antibiotika oder von Kombinationstherapie wird abgeraten.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Mittel der Wahl sind Doxycyclin oder Amoxicillin für 30 Tage. Falls mehrere Wochen nach initialer antibiotischer Therapie noch Beschwerden berichtet werden, kann ein weiterer Therapieversuch mit Ceftriaxon oder Cefotaxim für 14-21 Tage angedacht werden. Von der Durchführung weiterer Therapiezyklen, einer Langzeittherapie, einer Pulstherapie, dem Einsatz alternativer Antibiotika oder von Kombinationstherapie wird abgeraten.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{| class=&quot;MsoTableGrid&quot; border=&quot;1&quot; cellspacing=&quot;0&quot; cellpadding=&quot;0&quot; width=&quot;628&quot; style=&quot;box-sizing: inherit; border-collapse: collapse; border-spacing: 0px; background-color: rgb(255, 255, 255); font-size: 14px; font-family: &amp;amp;quot;Open Sans&amp;amp;quot;, Roboto, arial, sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: 2; text-align: start; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: 0px; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); text-size-adjust: auto; margin-left: -0.25pt; border: none;&quot;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{| class=&quot;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;wikitable sortable bs-exportable &lt;/ins&gt;MsoTableGrid&quot; border=&quot;1&quot; cellspacing=&quot;0&quot; cellpadding=&quot;0&quot; width=&quot;628&quot; style=&quot;box-sizing: inherit; border-collapse: collapse; border-spacing: 0px; background-color: rgb(255, 255, 255); font-size: 14px; font-family: &amp;amp;quot;Open Sans&amp;amp;quot;, Roboto, arial, sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: 2; text-align: start; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: 0px; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); text-size-adjust: auto; margin-left: -0.25pt; border: none;&quot;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| style=&amp;quot;background-color:rgb(191, 191, 191);width:80.85pt;&amp;quot; width=&amp;quot;108&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;Klinische Situation&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| style=&amp;quot;background-color:rgb(191, 191, 191);width:80.85pt;&amp;quot; width=&amp;quot;108&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;Klinische Situation&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;width:66.55pt;&amp;quot; width=&amp;quot;89&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Präferenz&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;width:66.55pt;&amp;quot; width=&amp;quot;89&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Präferenz&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l52&quot;&gt;Line 52:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 52:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Anders als bei der kutanen Borreliose kommt Azithromycin aufgrund der Möglichkeit der QT-Zeit Verlängerung, nicht als Therapiealternative in Frage.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Anders als bei der kutanen Borreliose kommt Azithromycin aufgrund der Möglichkeit der QT-Zeit Verlängerung, nicht als Therapiealternative in Frage.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{| class=&quot;MsoTableGrid&quot; border=&quot;1&quot; cellspacing=&quot;0&quot; cellpadding=&quot;0&quot; width=&quot;616&quot; style=&quot;box-sizing: inherit; border-collapse: collapse; border-spacing: 0px; background-color: rgb(255, 255, 255); font-size: 14px; font-family: &amp;amp;quot;Open Sans&amp;amp;quot;, Roboto, arial, sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: 2; text-align: start; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: 0px; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); text-size-adjust: auto; margin-left: -0.25pt; border: none;&quot;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{| class=&quot;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;wikitable sortable bs-exportable filterable &lt;/ins&gt;MsoTableGrid&quot; border=&quot;1&quot; cellspacing=&quot;0&quot; cellpadding=&quot;0&quot; width=&quot;616&quot; style=&quot;box-sizing: inherit; border-collapse: collapse; border-spacing: 0px; background-color: rgb(255, 255, 255); font-size: 14px; font-family: &amp;amp;quot;Open Sans&amp;amp;quot;, Roboto, arial, sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: 2; text-align: start; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: 0px; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); text-size-adjust: auto; margin-left: -0.25pt; border: none;&quot;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| style=&amp;quot;background-color:rgb(191, 191, 191);width:78.6pt;&amp;quot; width=&amp;quot;105&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;Klinische Situation&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| style=&amp;quot;background-color:rgb(191, 191, 191);width:78.6pt;&amp;quot; width=&amp;quot;105&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;Klinische Situation&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;width:66.5pt;&amp;quot; width=&amp;quot;89&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Präferenz&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;width:66.5pt;&amp;quot; width=&amp;quot;89&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Präferenz&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;

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&lt;/table&gt;</summary>
		<author><name>imported&gt;Bestem</name></author>
	</entry>
	<entry>
		<id>https://wiki.cakele.iodatalabs.dev/index.php?title=DGI:Lymeborreliose/Therapie&amp;diff=1136&amp;oldid=prev</id>
		<title>imported&gt;Brinkery at 13:41, 10 December 2020</title>
		<link rel="alternate" type="text/html" href="https://wiki.cakele.iodatalabs.dev/index.php?title=DGI:Lymeborreliose/Therapie&amp;diff=1136&amp;oldid=prev"/>
		<updated>2020-12-10T13:41:29Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 13:41, 10 December 2020&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== Therapie ==&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;==Therapie==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;br /&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;br /&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;==== &amp;lt;span style=&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;&amp;gt;Lyme Arthritis&amp;lt;/span&amp;gt; ====&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;====&amp;lt;span style=&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;&amp;gt;Lyme Arthritis&amp;lt;/span&amp;gt;====&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Die Prognose der Lyme-Arthritis kann mit einer ~ 80-90 %-igen Ansprechrate als positiv bewertet werden. Die Resolution der Arthritis kann mehrere Wochen bis Monate in Anspruch nehmen (bis zu 12 Monate). Etwa 10-20 % aller Patienten werden als therapierefraktär eingestuft und sprechen nicht auf eine antibiotische Therapie an. Hier eine Differentialdiagnose ist angezeigt.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Die Prognose der Lyme-Arthritis kann mit einer ~ 80-90 %-igen Ansprechrate als positiv bewertet werden. Die Resolution der Arthritis kann mehrere Wochen bis Monate in Anspruch nehmen (bis zu 12 Monate). Etwa 10-20 % aller Patienten werden als therapierefraktär eingestuft und sprechen nicht auf eine antibiotische Therapie an. Hier eine Differentialdiagnose ist angezeigt.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l46&quot;&gt;Line 46:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 46:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|}&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|}&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;==== &amp;lt;span style=&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;&amp;gt;Lyme-Karditis&amp;lt;/span&amp;gt; ====&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;====&amp;lt;span style=&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;&amp;gt;Lyme-Karditis&amp;lt;/span&amp;gt;====&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Insgesamt ist die Datenlage zur antibiotischen Therapie der Lyme Karditis schlecht.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Insgesamt ist die Datenlage zur antibiotischen Therapie der Lyme Karditis schlecht.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l92&quot;&gt;Line 92:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 92:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|}&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|}&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;==== Post-Treatment-Lyme-Disease-Syndrome ====&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;====Post-Treatment-Lyme-Disease-Syndrome====&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Bei fehlendem Nachweis einer (Re-)Infektion oder fehlender Kenntnis eines Therapieversagens soll keine weitere antibiotische Therapie angestrebt werden. Studien geben nicht nur keinen Hinweis auf einen Benefit hinsichtlich des outcomes für die Patienten, sondern sogar nachteilige Effekt [6], die in einer negativen Nutzen-Risiko-Bewertung für die antibiotische Therapie münden. Von einer antibiotischen Therapie wird daher abgeraten.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Bei fehlendem Nachweis einer (Re-)Infektion oder fehlender Kenntnis eines Therapieversagens soll keine weitere antibiotische Therapie angestrebt werden. Studien geben nicht nur keinen Hinweis auf einen Benefit hinsichtlich des outcomes für die Patienten, sondern sogar nachteilige Effekt [6], die in einer negativen Nutzen-Risiko-Bewertung für die antibiotische Therapie münden. Von einer antibiotischen Therapie wird daher abgeraten.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Eine Therapie der PTLDS sollte nach symptomorientierten Gesichtspunkten erfolgen und eine Differentialdiagnostik angestrebt werden.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Eine Therapie der PTLDS sollte nach symptomorientierten Gesichtspunkten erfolgen und eine Differentialdiagnostik angestrebt werden.&amp;lt;/span&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt; &lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;br &lt;/ins&gt;/&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;span style=&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;&amp;gt;[1] Hofmann H, et al. &#039;&#039;S2k-Leitlinie Kutane Lyme Borreliose&#039;&#039;, 2016&amp;lt;/span&amp;gt;&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-added&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt; &lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-added&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;span style=&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;&amp;gt;[2] Rauer S, Kastenbauer S. &#039;&#039;S3-Leitlinie Neuroborreliose&#039;&#039;, 2018&amp;lt;/span&amp;gt;&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-added&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt; &lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-added&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[3] Kullberg BJ, et al., &#039;&#039;Lyme borreliosis: diagnosis and treatment.&#039;&#039; &amp;lt;span style=&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;&amp;gt;BMJ, 2020. 369:m1041. &amp;lt;span style=&quot;color: black&quot;&amp;gt;doi: 10.1136/bmj.m1041.&amp;lt;/span&amp;gt; &amp;lt;span style=&quot;box-sizing: inherit;&quot;&amp;gt; &amp;lt;/span&amp;gt;&amp;lt;/span&amp;gt;&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-added&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt; &lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-added&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;span style=&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;&amp;gt;[4] Gaubitz M, et al., &#039;&#039;Empfehlungen der DGRh zur Therapie der Lyme-Borreliose, speziell des Erythema migrans sowie der Lyme-Arthritis&#039;&#039;, 2012&amp;lt;/span&amp;gt;&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-added&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt; &lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-added&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[5] NICE guideline 2018: &#039;&#039;Lyme disease&#039;&#039;&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-added&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt; &lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-added&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[6] Goodlet KJ, Fairman KA. &#039;&#039;Adverse Events Associated With Antibiotics and Intravenous Therapies for Post–Lyme Disease Syndrome in a Commercially Insured Sample.&#039;&#039; &amp;lt;span style=&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;&amp;gt;Clin Infect Dis, 2018; 67(10):1568-1574&lt;/del&gt;&amp;lt;/&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;span&lt;/del&gt;&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-added&quot;&gt;&lt;/td&gt;&lt;/tr&gt;

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		<author><name>imported&gt;Brinkery</name></author>
	</entry>
	<entry>
		<id>https://wiki.cakele.iodatalabs.dev/index.php?title=DGI:Lymeborreliose/Therapie&amp;diff=1135&amp;oldid=prev</id>
		<title>imported&gt;Brinkery: Die Seite wurde neu angelegt: „== Therapie == &lt;br /&gt;  ==== &lt;span style=&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;&gt;Lyme Arthritis&lt;/span&gt; ==== &lt;span style=&quot;box-sizing: inherit; fon…“</title>
		<link rel="alternate" type="text/html" href="https://wiki.cakele.iodatalabs.dev/index.php?title=DGI:Lymeborreliose/Therapie&amp;diff=1135&amp;oldid=prev"/>
		<updated>2020-12-10T13:03:40Z</updated>

		<summary type="html">&lt;p&gt;Die Seite wurde neu angelegt: „== Therapie == &amp;lt;br /&amp;gt;  ==== &amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Lyme Arthritis&amp;lt;/span&amp;gt; ==== &amp;lt;span style=&amp;quot;box-sizing: inherit; fon…“&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;== Therapie ==&lt;br /&gt;
&amp;lt;br /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==== &amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Lyme Arthritis&amp;lt;/span&amp;gt; ====&lt;br /&gt;
&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Die Prognose der Lyme-Arthritis kann mit einer ~ 80-90 %-igen Ansprechrate als positiv bewertet werden. Die Resolution der Arthritis kann mehrere Wochen bis Monate in Anspruch nehmen (bis zu 12 Monate). Etwa 10-20 % aller Patienten werden als therapierefraktär eingestuft und sprechen nicht auf eine antibiotische Therapie an. Hier eine Differentialdiagnose ist angezeigt.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Mittel der Wahl sind Doxycyclin oder Amoxicillin für 30 Tage. Falls mehrere Wochen nach initialer antibiotischer Therapie noch Beschwerden berichtet werden, kann ein weiterer Therapieversuch mit Ceftriaxon oder Cefotaxim für 14-21 Tage angedacht werden. Von der Durchführung weiterer Therapiezyklen, einer Langzeittherapie, einer Pulstherapie, dem Einsatz alternativer Antibiotika oder von Kombinationstherapie wird abgeraten.&amp;lt;/span&amp;gt;&lt;br /&gt;
{| class=&amp;quot;MsoTableGrid&amp;quot; border=&amp;quot;1&amp;quot; cellspacing=&amp;quot;0&amp;quot; cellpadding=&amp;quot;0&amp;quot; width=&amp;quot;628&amp;quot; style=&amp;quot;box-sizing: inherit; border-collapse: collapse; border-spacing: 0px; background-color: rgb(255, 255, 255); font-size: 14px; font-family: &amp;amp;quot;Open Sans&amp;amp;quot;, Roboto, arial, sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: 2; text-align: start; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: 0px; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); text-size-adjust: auto; margin-left: -0.25pt; border: none;&amp;quot;&lt;br /&gt;
| style=&amp;quot;background-color:rgb(191, 191, 191);width:80.85pt;&amp;quot; width=&amp;quot;108&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;Klinische Situation&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;width:66.55pt;&amp;quot; width=&amp;quot;89&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Präferenz&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;width:64.1pt;&amp;quot; width=&amp;quot;85&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Substanz&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;width:76.25pt;&amp;quot; width=&amp;quot;102&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Dosierung&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;width:55.85pt;&amp;quot; width=&amp;quot;74&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Dauer&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;width:62.05pt;&amp;quot; width=&amp;quot;83&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Anpassun-gen&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;width:65.25pt;&amp;quot; width=&amp;quot;87&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Kommentar&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
|- style=&amp;quot;box-sizing: inherit;&amp;quot;&lt;br /&gt;
| rowspan=&amp;quot;2&amp;quot; style=&amp;quot;border-left-width:1pt;border-right-width:1pt;border-bottom-width:1pt;border-left-color:windowtext;border-right-color:windowtext;border-bottom-color:windowtext;width:80.85pt;&amp;quot; width=&amp;quot;108&amp;quot; valign=&amp;quot;top&amp;quot; |Lyme Arthtirtis&lt;br /&gt;
| rowspan=&amp;quot;2&amp;quot; style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:66.55pt;&amp;quot; width=&amp;quot;89&amp;quot; valign=&amp;quot;top&amp;quot; |Therapie der Wahl&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-right-color:windowtext;width:64.1pt;&amp;quot; width=&amp;quot;85&amp;quot; valign=&amp;quot;top&amp;quot; |Doxycyclin&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;ODER&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-right-color:windowtext;width:76.25pt;&amp;quot; width=&amp;quot;102&amp;quot; valign=&amp;quot;top&amp;quot; |200 mg q24h p.o.&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-right-color:windowtext;width:55.85pt;&amp;quot; width=&amp;quot;74&amp;quot; valign=&amp;quot;top&amp;quot; |30 d&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-right-color:windowtext;width:62.05pt;&amp;quot; width=&amp;quot;83&amp;quot; valign=&amp;quot;top&amp;quot; | -&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-right-color:windowtext;width:65.25pt;&amp;quot; width=&amp;quot;87&amp;quot; valign=&amp;quot;top&amp;quot; |Für Jugendliche und Erwachsene ab 50 kg&lt;br /&gt;
|- style=&amp;quot;box-sizing: inherit;&amp;quot;&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:64.1pt;&amp;quot; width=&amp;quot;85&amp;quot; valign=&amp;quot;top&amp;quot; |Amoxicillin&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:76.25pt;&amp;quot; width=&amp;quot;102&amp;quot; valign=&amp;quot;top&amp;quot; |1 g &amp;lt;span style=&amp;quot;box-sizing: inherit;&amp;quot;&amp;gt;&amp;lt;span class=&amp;quot;Apple-converted-space&amp;quot; style=&amp;quot;box-sizing: inherit;&amp;quot;&amp;gt; &amp;lt;/span&amp;gt;&amp;lt;/span&amp;gt;q8h p.o.&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:55.85pt;&amp;quot; width=&amp;quot;74&amp;quot; valign=&amp;quot;top&amp;quot; |30 d&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:62.05pt;&amp;quot; width=&amp;quot;83&amp;quot; valign=&amp;quot;top&amp;quot; | -&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:65.25pt;&amp;quot; width=&amp;quot;87&amp;quot; valign=&amp;quot;top&amp;quot; | -&lt;br /&gt;
|- style=&amp;quot;box-sizing: inherit;&amp;quot;&lt;br /&gt;
| rowspan=&amp;quot;2&amp;quot; style=&amp;quot;border-left-width:1pt;border-right-width:1pt;border-bottom-width:1pt;border-left-color:windowtext;border-right-color:windowtext;border-bottom-color:windowtext;width:80.85pt;&amp;quot; width=&amp;quot;108&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;Initial therapierefraktäre Lyme-Arthritis&amp;#039;&amp;#039;&lt;br /&gt;
| rowspan=&amp;quot;2&amp;quot; style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:66.55pt;&amp;quot; width=&amp;quot;89&amp;quot; valign=&amp;quot;top&amp;quot; |Therapie der Wahl&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-right-color:windowtext;width:64.1pt;&amp;quot; width=&amp;quot;85&amp;quot; valign=&amp;quot;top&amp;quot; |Ceftriaxon&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;ODER&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-right-color:windowtext;width:76.25pt;&amp;quot; width=&amp;quot;102&amp;quot; valign=&amp;quot;top&amp;quot; |2 g q24h i.v.&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-right-color:windowtext;width:55.85pt;&amp;quot; width=&amp;quot;74&amp;quot; valign=&amp;quot;top&amp;quot; |14-21 d&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-right-color:windowtext;width:62.05pt;&amp;quot; width=&amp;quot;83&amp;quot; valign=&amp;quot;top&amp;quot; | -&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-right-color:windowtext;width:65.25pt;&amp;quot; width=&amp;quot;87&amp;quot; valign=&amp;quot;top&amp;quot; | -&lt;br /&gt;
|- style=&amp;quot;box-sizing: inherit;&amp;quot;&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:64.1pt;&amp;quot; width=&amp;quot;85&amp;quot; valign=&amp;quot;top&amp;quot; |Cefotaxim&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:76.25pt;&amp;quot; width=&amp;quot;102&amp;quot; valign=&amp;quot;top&amp;quot; |2 g q8h i.v.&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:55.85pt;&amp;quot; width=&amp;quot;74&amp;quot; valign=&amp;quot;top&amp;quot; |14-21 d&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:62.05pt;&amp;quot; width=&amp;quot;83&amp;quot; valign=&amp;quot;top&amp;quot; | -&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:65.25pt;&amp;quot; width=&amp;quot;87&amp;quot; valign=&amp;quot;top&amp;quot; | -&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
==== &amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Lyme-Karditis&amp;lt;/span&amp;gt; ====&lt;br /&gt;
&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Insgesamt ist die Datenlage zur antibiotischen Therapie der Lyme Karditis schlecht.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Die Therapiedauer wird mit 21 Tagen empfohlen, kann aber auf 30 Tage eskaliert werden. Die Substanzwahl umfasst bei hämodynamisch stabilen Patienten Doxycyclin oder Amoxicillin, bzw. Ceftriaxon als Alternativtherapeutikum. Hämodynamisch instabile Patienten sollten unmittelbar mit Ceftriaxon behandelt werden.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Anders als bei der kutanen Borreliose kommt Azithromycin aufgrund der Möglichkeit der QT-Zeit Verlängerung, nicht als Therapiealternative in Frage.&amp;lt;/span&amp;gt;&lt;br /&gt;
{| class=&amp;quot;MsoTableGrid&amp;quot; border=&amp;quot;1&amp;quot; cellspacing=&amp;quot;0&amp;quot; cellpadding=&amp;quot;0&amp;quot; width=&amp;quot;616&amp;quot; style=&amp;quot;box-sizing: inherit; border-collapse: collapse; border-spacing: 0px; background-color: rgb(255, 255, 255); font-size: 14px; font-family: &amp;amp;quot;Open Sans&amp;amp;quot;, Roboto, arial, sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: 2; text-align: start; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: 0px; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); text-size-adjust: auto; margin-left: -0.25pt; border: none;&amp;quot;&lt;br /&gt;
| style=&amp;quot;background-color:rgb(191, 191, 191);width:78.6pt;&amp;quot; width=&amp;quot;105&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;Klinische Situation&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;width:66.5pt;&amp;quot; width=&amp;quot;89&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Präferenz&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;width:64.1pt;&amp;quot; width=&amp;quot;85&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Substanz&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;width:75.55pt;&amp;quot; width=&amp;quot;101&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Dosierung&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;width:49.6pt;&amp;quot; width=&amp;quot;66&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Dauer&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;width:62.05pt;&amp;quot; width=&amp;quot;83&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Anpassun-gen&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
| style=&amp;quot;background-color:rgb(191, 191, 191);border-right-width:1pt;border-top-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-top-color:windowtext;border-bottom-color:windowtext;width:65.25pt;&amp;quot; width=&amp;quot;87&amp;quot; valign=&amp;quot;top&amp;quot; |&amp;#039;&amp;#039;&amp;#039;&amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;Kommentar&amp;lt;/span&amp;gt;&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
|- style=&amp;quot;box-sizing: inherit;&amp;quot;&lt;br /&gt;
| rowspan=&amp;quot;3&amp;quot; style=&amp;quot;border-left-width:1pt;border-right-width:1pt;border-bottom-width:1pt;border-left-color:windowtext;border-right-color:windowtext;border-bottom-color:windowtext;width:78.6pt;&amp;quot; width=&amp;quot;105&amp;quot; valign=&amp;quot;top&amp;quot; |Lyme Karditis (hämo-dynamisch stabil)&lt;br /&gt;
| rowspan=&amp;quot;2&amp;quot; style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:66.5pt;&amp;quot; width=&amp;quot;89&amp;quot; valign=&amp;quot;top&amp;quot; |Therapie der Wahl&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-right-color:windowtext;width:64.1pt;&amp;quot; width=&amp;quot;85&amp;quot; valign=&amp;quot;top&amp;quot; |Doxycyclin&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;ODER&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-right-color:windowtext;width:75.55pt;&amp;quot; width=&amp;quot;101&amp;quot; valign=&amp;quot;top&amp;quot; |200 mg q24h p.o.&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-right-color:windowtext;width:49.6pt;&amp;quot; width=&amp;quot;66&amp;quot; valign=&amp;quot;top&amp;quot; |21 d&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-right-color:windowtext;width:62.05pt;&amp;quot; width=&amp;quot;83&amp;quot; valign=&amp;quot;top&amp;quot; | -&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-right-color:windowtext;width:65.25pt;&amp;quot; width=&amp;quot;87&amp;quot; valign=&amp;quot;top&amp;quot; |Für Jugendliche und Erwachsene ab 50 kg&lt;br /&gt;
|- style=&amp;quot;box-sizing: inherit;&amp;quot;&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:64.1pt;&amp;quot; width=&amp;quot;85&amp;quot; valign=&amp;quot;top&amp;quot; |Amoxicillin&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:75.55pt;&amp;quot; width=&amp;quot;101&amp;quot; valign=&amp;quot;top&amp;quot; |1 g &amp;lt;span style=&amp;quot;box-sizing: inherit;&amp;quot;&amp;gt;&amp;lt;span class=&amp;quot;Apple-converted-space&amp;quot; style=&amp;quot;box-sizing: inherit;&amp;quot;&amp;gt; &amp;lt;/span&amp;gt;&amp;lt;/span&amp;gt;q8h p.o.&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:49.6pt;&amp;quot; width=&amp;quot;66&amp;quot; valign=&amp;quot;top&amp;quot; |21 d&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:62.05pt;&amp;quot; width=&amp;quot;83&amp;quot; valign=&amp;quot;top&amp;quot; | -&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:65.25pt;&amp;quot; width=&amp;quot;87&amp;quot; valign=&amp;quot;top&amp;quot; |&lt;br /&gt;
|- style=&amp;quot;box-sizing: inherit;&amp;quot;&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:66.5pt;&amp;quot; width=&amp;quot;89&amp;quot; valign=&amp;quot;top&amp;quot; |Alternative&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:64.1pt;&amp;quot; width=&amp;quot;85&amp;quot; valign=&amp;quot;top&amp;quot; |Ceftriaxon&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:75.55pt;&amp;quot; width=&amp;quot;101&amp;quot; valign=&amp;quot;top&amp;quot; |2 g q24 h i.v.&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:49.6pt;&amp;quot; width=&amp;quot;66&amp;quot; valign=&amp;quot;top&amp;quot; |21 d&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:62.05pt;&amp;quot; width=&amp;quot;83&amp;quot; valign=&amp;quot;top&amp;quot; | -&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:65.25pt;&amp;quot; width=&amp;quot;87&amp;quot; valign=&amp;quot;top&amp;quot; | -&lt;br /&gt;
|- style=&amp;quot;box-sizing: inherit;&amp;quot;&lt;br /&gt;
| style=&amp;quot;border-left-width:1pt;border-right-width:1pt;border-bottom-width:1pt;border-left-color:windowtext;border-right-color:windowtext;border-bottom-color:windowtext;width:78.6pt;&amp;quot; width=&amp;quot;105&amp;quot; valign=&amp;quot;top&amp;quot; |Lyme Karditis (hämo-dynamisch instabil)&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:66.5pt;&amp;quot; width=&amp;quot;89&amp;quot; valign=&amp;quot;top&amp;quot; |Therapie der Wahl&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:64.1pt;&amp;quot; width=&amp;quot;85&amp;quot; valign=&amp;quot;top&amp;quot; |Ceftriaxon&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:75.55pt;&amp;quot; width=&amp;quot;101&amp;quot; valign=&amp;quot;top&amp;quot; |2 g q24h i.v.&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:49.6pt;&amp;quot; width=&amp;quot;66&amp;quot; valign=&amp;quot;top&amp;quot; |21 d&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:62.05pt;&amp;quot; width=&amp;quot;83&amp;quot; valign=&amp;quot;top&amp;quot; | -&lt;br /&gt;
| style=&amp;quot;border-right-width:1pt;border-bottom-width:1pt;border-right-color:windowtext;border-bottom-color:windowtext;width:65.25pt;&amp;quot; width=&amp;quot;87&amp;quot; valign=&amp;quot;top&amp;quot; | -&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
==== Post-Treatment-Lyme-Disease-Syndrome ====&lt;br /&gt;
&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Bei fehlendem Nachweis einer (Re-)Infektion oder fehlender Kenntnis eines Therapieversagens soll keine weitere antibiotische Therapie angestrebt werden. Studien geben nicht nur keinen Hinweis auf einen Benefit hinsichtlich des outcomes für die Patienten, sondern sogar nachteilige Effekt [6], die in einer negativen Nutzen-Risiko-Bewertung für die antibiotische Therapie münden. Von einer antibiotischen Therapie wird daher abgeraten.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Eine Therapie der PTLDS sollte nach symptomorientierten Gesichtspunkten erfolgen und eine Differentialdiagnostik angestrebt werden.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;[1] Hofmann H, et al. &amp;#039;&amp;#039;S2k-Leitlinie Kutane Lyme Borreliose&amp;#039;&amp;#039;, 2016&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;[2] Rauer S, Kastenbauer S. &amp;#039;&amp;#039;S3-Leitlinie Neuroborreliose&amp;#039;&amp;#039;, 2018&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
[3] Kullberg BJ, et al., &amp;#039;&amp;#039;Lyme borreliosis: diagnosis and treatment.&amp;#039;&amp;#039; &amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;BMJ, 2020. 369:m1041. &amp;lt;span style=&amp;quot;color: black&amp;quot;&amp;gt;doi: 10.1136/bmj.m1041.&amp;lt;/span&amp;gt; &amp;lt;span style=&amp;quot;box-sizing: inherit;&amp;quot;&amp;gt; &amp;lt;/span&amp;gt;&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;[4] Gaubitz M, et al., &amp;#039;&amp;#039;Empfehlungen der DGRh zur Therapie der Lyme-Borreliose, speziell des Erythema migrans sowie der Lyme-Arthritis&amp;#039;&amp;#039;, 2012&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
[5] NICE guideline 2018: &amp;#039;&amp;#039;Lyme disease&amp;#039;&amp;#039;&lt;br /&gt;
&lt;br /&gt;
[6] Goodlet KJ, Fairman KA. &amp;#039;&amp;#039;Adverse Events Associated With Antibiotics and Intravenous Therapies for Post–Lyme Disease Syndrome in a Commercially Insured Sample.&amp;#039;&amp;#039; &amp;lt;span style=&amp;quot;box-sizing: inherit; font-family: Arial, sans-serif;&amp;quot;&amp;gt;Clin Infect Dis, 2018; 67(10):1568-1574&amp;lt;/span&amp;gt;&lt;/div&gt;</summary>
		<author><name>imported&gt;Brinkery</name></author>
	</entry>
</feed>