imported>WikiSysop at 06:49, 4 June 2020

2020-06-04T06:49:36Z

← Older revision		Revision as of 06:49, 4 June 2020
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	Jedoch kann eine Sepsis auch durch saisonale Influenza/Grippe-Viren, Dengue-Viren und andere Erreger, wie Vogel- und Schweinegrippeviren, Coronaviren und in jüngster Zeit Ebola- und Gelbfieber-Viren bedingt sein.		Jedoch kann eine Sepsis auch durch saisonale Influenza/Grippe-Viren, Dengue-Viren und andere Erreger, wie Vogel- und Schweinegrippeviren, Coronaviren und in jüngster Zeit Ebola- und Gelbfieber-Viren bedingt sein.

			Kommentare
			<references group="mehr" />

	==Therapie==		==Therapie==

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	<span class="ve-pasteProtect" style="mso-list:Ignore" data-ve-attributes="{"style":"mso-list:Ignore"}">3.<span class="ve-pasteProtect" style="font:7.0pt "Times New Roman"" data-ve-attributes="{"style":"font:7.0pt \"Times New Roman\""}"> </span></span>Lachmann, G., La Rosée, P., Schenk, T. et al. Anaesthesist (2016) 65: 776. <nowiki>https://doi.org/10.1007/s00101-016-0216-x</nowiki><br />		<span class="ve-pasteProtect" style="mso-list:Ignore" data-ve-attributes="{"style":"mso-list:Ignore"}">3.<span class="ve-pasteProtect" style="font:7.0pt "Times New Roman"" data-ve-attributes="{"style":"font:7.0pt \"Times New Roman\""}"> </span></span>Lachmann, G., La Rosée, P., Schenk, T. et al. Anaesthesist (2016) 65: 776. <nowiki>https://doi.org/10.1007/s00101-016-0216-x</nowiki><br />
	<references />		<references />
			<references group="mehr" />

imported>WikiSysop at 06:45, 4 June 2020

2020-06-04T06:45:54Z

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imported>Bestem: Tabelle und Einzelnachweise

2020-04-09T10:59:08Z

Tabelle und Einzelnachweise

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imported>Bestem at 10:44, 9 April 2020

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imported>Bestem at 12:07, 3 April 2020

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imported>Bestem at 12:04, 3 April 2020

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imported>Bestem at 15:18, 2 April 2020

2020-04-02T15:18:52Z

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	<sup><span style="color: black">4)</span></sup> <span style="color: black">IIV: nur in Ausnahmefällen!, TDM Vancomycin intermittierende Gabe (Infusionsdauer: mind. 1 h/Gabe, um Red-Man-Syndrom zu vermeiden):</span> ~~<span style="color: black">à</span~~><span style="color: black">Ziel-Talspiegel 15-20 mg/l</span>		<sup><span style="color: black">4)</span></sup> <span style="color: black">IIV: nur in Ausnahmefällen!, TDM Vancomycin intermittierende Gabe (Infusionsdauer: mind. 1 h/Gabe, um Red-Man-Syndrom zu vermeiden):</span> -> <span style="color: black">Ziel-Talspiegel 15-20 mg/l</span>

imported>Bestem at 15:16, 2 April 2020

2020-04-02T15:16:28Z

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	\|>90 kg		\|>90 kg
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	<span style="color: black">->TDM Vancomycin kontinuierliche Gabe: Ziel-Spiegel steady state 25-30 mg/l</span>		<span style="color: black">->TDM Vancomycin kontinuierliche Gabe: Ziel-Spiegel steady state 25-30 mg/l</span>

imported>Bestem: Übertragung aus der PDF Datei abgeschlossen. Evtl. noch Schriftgröße anpassen, sonst fertig

2020-04-02T12:37:08Z

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← Older revision		Revision as of 12:04, 3 April 2020
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	''S. aureus, Enterobacteriaceae, Pseudomonas aeruginosa''<sup style="box-sizing: inherit; color: rgb(51, 51, 51); font-family: &quot;Open Sans&quot;,&quot;Roboto&quot;,&quot;arial&quot;,sans-serif; font-size: 75%; font-style: normal; font-variant: normal; font-weight: 400; height: 1px; letter-spacing: normal; line-height: 1; orphans: 2; position: relative; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; top: -0.5em; vertical-align: baseline; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;" data-ve-attributes="{"style":"box-sizing: inherit; color: rgb(51, 51, 51); font-family: &quot;Open Sans&quot;,&quot;Roboto&quot;,&quot;arial&quot;,sans-serif; font-size: 75%; font-style: normal; font-variant: normal; font-weight: 400; height: 1px; letter-spacing: normal; line-height: 1; orphans: 2; position: relative; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; top: -0.5em; vertical-align: baseline; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;"}"><span class="ve-pasteProtect" style="color: black" data-ve-attributes="{"style":"color: black"}">3)</span></sup><ref name=":0">3) Bei Sepsis/ septischer Schock sollte eine '''prolongierte''' Gabe (=Infusionsdauer: 3-4h/Dosis) der ß-Laktam-Antibiotika nach einer initialen Standardosis (Bolus) angestrebt werden. Bei Verfügbarkeit eines TDM ist eine kontinuierliche Gabe der ß-Laktam-Antibiotika (ebenfalls '''nach''' einer initalen Standarddosis (Bolus)) möglich.		''S. aureus, Enterobacteriaceae, Pseudomonas aeruginosa''<sup style="box-sizing: inherit; color: rgb(51, 51, 51); font-family: &quot;Open Sans&quot;,&quot;Roboto&quot;,&quot;arial&quot;,sans-serif; font-size: 75%; font-style: normal; font-variant: normal; font-weight: 400; height: 1px; letter-spacing: normal; line-height: 1; orphans: 2; position: relative; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; top: -0.5em; vertical-align: baseline; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;" data-ve-attributes="{"style":"box-sizing: inherit; color: rgb(51, 51, 51); font-family: &quot;Open Sans&quot;,&quot;Roboto&quot;,&quot;arial&quot;,sans-serif; font-size: 75%; font-style: normal; font-variant: normal; font-weight: 400; height: 1px; letter-spacing: normal; line-height: 1; orphans: 2; position: relative; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; top: -0.5em; vertical-align: baseline; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;"}"><span class="ve-pasteProtect" style="color: black" data-ve-attributes="{"style":"color: black"}">3)</span></sup><ref name=":0">3) Bei Sepsis/ septischer Schock sollte eine '''prolongierte''' Gabe (=Infusionsdauer: 3-4h/Dosis) der ß-Laktam-Antibiotika nach einer initialen Standardosis (Bolus) angestrebt werden. Bei Verfügbarkeit eines TDM ist eine kontinuierliche Gabe der ß-Laktam-Antibiotika (ebenfalls '''nach''' einer initalen Standarddosis (Bolus)) möglich.

	->typisches TDM Ziel steady state Piperacillin/Tazobactam: 32-64 mg/l		->typisches TDM Ziel steady state Piperacillin/Tazobactam: 32-64 mg/l

	->typisches TDM Ziel steady state Meropenem: 8-16 mg/l</ref>		->typisches TDM Ziel steady state Meropenem: 8-16 mg/l</ref>
	\|- style="height:80.75ptpx;" data-ve-attributes="{"style":"height:80.75ptpx;"}"		\|- style="height:80.75ptpx;" data-ve-attributes="{"style":"height:80.75ptpx;"}"
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	\| style="width:269.3pt;" width="359" valign="top" data-ve-attributes="{"style":"width:269.3pt;"}" \|''S. aureus, E. coli,''		\| style="width:269.3pt;" width="359" valign="top" data-ve-attributes="{"style":"width:269.3pt;"}" \|''S. aureus, E. coli,''

	''andere Enterobacteriaceae, Pseudomonas aeruginosa''<sup style="box-sizing: inherit; color: rgb(51, 51, 51); font-family: &quot;Open Sans&quot;,&quot;Roboto&quot;,&quot;arial&quot;,sans-serif; font-size: 75%; font-style: normal; font-variant: normal; font-weight: 400; height: 1px; letter-spacing: normal; line-height: 1; orphans: 2; position: relative; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; top: -0.5em; vertical-align: baseline; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;" data-ve-attributes="{"style":"box-sizing: inherit; color: rgb(51, 51, 51); font-family: &quot;Open Sans&quot;,&quot;Roboto&quot;,&quot;arial&quot;,sans-serif; font-size: 75%; font-style: normal; font-variant: normal; font-weight: 400; height: 1px; letter-spacing: normal; line-height: 1; orphans: 2; position: relative; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; top: -0.5em; vertical-align: baseline; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;"}"><span class="ve-pasteProtect" style="color: black" data-ve-attributes="{"style":"color: black"}">3)</span></sup><ref name=":1"~~>2) Dosierungsangaben für erwachsene Patienten mit normaler bis kompensierter Nierenfunktion (GFR > 50 ml~~/~~min)<br /></ref~~>'', Anaerobier''		''andere Enterobacteriaceae, Pseudomonas aeruginosa''<sup style="box-sizing: inherit; color: rgb(51, 51, 51); font-family: &quot;Open Sans&quot;,&quot;Roboto&quot;,&quot;arial&quot;,sans-serif; font-size: 75%; font-style: normal; font-variant: normal; font-weight: 400; height: 1px; letter-spacing: normal; line-height: 1; orphans: 2; position: relative; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; top: -0.5em; vertical-align: baseline; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;" data-ve-attributes="{"style":"box-sizing: inherit; color: rgb(51, 51, 51); font-family: &quot;Open Sans&quot;,&quot;Roboto&quot;,&quot;arial&quot;,sans-serif; font-size: 75%; font-style: normal; font-variant: normal; font-weight: 400; height: 1px; letter-spacing: normal; line-height: 1; orphans: 2; position: relative; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; top: -0.5em; vertical-align: baseline; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;"}"><span class="ve-pasteProtect" style="color: black" data-ve-attributes="{"style":"color: black"}">3)</span></sup><ref name=":0" />'', Anaerobier''
	\|- style="height:47.05ptpx;" data-ve-attributes="{"style":"height:47.05ptpx;"}"		\|- style="height:47.05ptpx;" data-ve-attributes="{"style":"height:47.05ptpx;"}"
	\| style="vertical-align:middle;text-align:center;width:184.25pt;" width="246" valign="top" data-ve-attributes="{"style":"width:184.25pt;"}" \|'''Harnwege'''		\| style="vertical-align:middle;text-align:center;width:184.25pt;" width="246" valign="top" data-ve-attributes="{"style":"width:184.25pt;"}" \|'''Harnwege'''
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	\| style="vertical-align:middle;text-align:center;width:102.9pt;" width="137" valign="top" data-ve-attributes="{"style":"width:102.9pt;"}" \|'''Erreger'''		\| style="vertical-align:middle;text-align:center;width:102.9pt;" width="137" valign="top" data-ve-attributes="{"style":"width:102.9pt;"}" \|'''Erreger'''
	\| style="vertical-align:middle;text-align:center;width:106.85pt;" width="142" valign="top" data-ve-attributes="{"style":"width:106.85pt;"}" \|'''Therapieerweiterung empfohlen mit'''		\| style="vertical-align:middle;text-align:center;width:106.85pt;" width="142" valign="top" data-ve-attributes="{"style":"width:106.85pt;"}" \|'''Therapieerweiterung empfohlen mit'''
	\| style="vertical-align:middle;text-align:center;width:112.3pt;" width="150" valign="top" data-ve-attributes="{"style":"width:112.3pt;"}" \|'''Dosierung<sup style="box-sizing: inherit; color: rgb(51, 51, 51); font-family: &quot;Open Sans&quot;,&quot;Roboto&quot;,&quot;arial&quot;,sans-serif; font-size: 75%; font-style: normal; font-variant: normal; font-weight: 400; height: 1px; letter-spacing: normal; line-height: 1; orphans: 2; position: relative; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; top: -0.5em; vertical-align: baseline; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;" data-ve-attributes="{"style":"box-sizing: inherit; color: rgb(51, 51, 51); font-family: &quot;Open Sans&quot;,&quot;Roboto&quot;,&quot;arial&quot;,sans-serif; font-size: 75%; font-style: normal; font-variant: normal; font-weight: 400; height: 1px; letter-spacing: normal; line-height: 1; orphans: 2; position: relative; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; top: -0.5em; vertical-align: baseline; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;"}"><span class="ve-pasteProtect" style="color: black" data-ve-attributes="{"style":"color: black"}">2)</span></sup>'''<ref name=":1" />		\| style="vertical-align:middle;text-align:center;width:112.3pt;" width="150" valign="top" data-ve-attributes="{"style":"width:112.3pt;"}" \|'''Dosierung<sup style="box-sizing: inherit; color: rgb(51, 51, 51); font-family: &quot;Open Sans&quot;,&quot;Roboto&quot;,&quot;arial&quot;,sans-serif; font-size: 75%; font-style: normal; font-variant: normal; font-weight: 400; height: 1px; letter-spacing: normal; line-height: 1; orphans: 2; position: relative; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; top: -0.5em; vertical-align: baseline; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;" data-ve-attributes="{"style":"box-sizing: inherit; color: rgb(51, 51, 51); font-family: &quot;Open Sans&quot;,&quot;Roboto&quot;,&quot;arial&quot;,sans-serif; font-size: 75%; font-style: normal; font-variant: normal; font-weight: 400; height: 1px; letter-spacing: normal; line-height: 1; orphans: 2; position: relative; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; top: -0.5em; vertical-align: baseline; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;"}"><span class="ve-pasteProtect" style="color: black" data-ve-attributes="{"style":"color: black"}">2)</span></sup>'''<ref name=":1">2) Dosierungsangaben für erwachsene Patienten mit normaler bis kompensierter Nierenfunktion (GFR > 50 ml/min)<br /></ref>
	\| style="vertical-align:middle;text-align:center;width:145.6pt;" width="194" valign="top" data-ve-attributes="{"style":"width:145.6pt;"}" \|'''Bemerkung<sup style="box-sizing: inherit; color: rgb(51, 51, 51); font-family: &quot;Open Sans&quot;,&quot;Roboto&quot;,&quot;arial&quot;,sans-serif; font-size: 75%; font-style: normal; font-variant: normal; font-weight: 400; height: 1px; letter-spacing: normal; line-height: 1; orphans: 2; position: relative; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; top: -0.5em; vertical-align: baseline; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;" data-ve-attributes="{"style":"box-sizing: inherit; color: rgb(51, 51, 51); font-family: &quot;Open Sans&quot;,&quot;Roboto&quot;,&quot;arial&quot;,sans-serif; font-size: 75%; font-style: normal; font-variant: normal; font-weight: 400; height: 1px; letter-spacing: normal; line-height: 1; orphans: 2; position: relative; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; top: -0.5em; vertical-align: baseline; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;"}"><span class="ve-pasteProtect" style="color: black" data-ve-attributes="{"style":"color: black"}">3)</span></sup>'''<ref name=":0" />		\| style="vertical-align:middle;text-align:center;width:145.6pt;" width="194" valign="top" data-ve-attributes="{"style":"width:145.6pt;"}" \|'''Bemerkung<sup style="box-sizing: inherit; color: rgb(51, 51, 51); font-family: &quot;Open Sans&quot;,&quot;Roboto&quot;,&quot;arial&quot;,sans-serif; font-size: 75%; font-style: normal; font-variant: normal; font-weight: 400; height: 1px; letter-spacing: normal; line-height: 1; orphans: 2; position: relative; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; top: -0.5em; vertical-align: baseline; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;" data-ve-attributes="{"style":"box-sizing: inherit; color: rgb(51, 51, 51); font-family: &quot;Open Sans&quot;,&quot;Roboto&quot;,&quot;arial&quot;,sans-serif; font-size: 75%; font-style: normal; font-variant: normal; font-weight: 400; height: 1px; letter-spacing: normal; line-height: 1; orphans: 2; position: relative; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; top: -0.5em; vertical-align: baseline; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;"}"><span class="ve-pasteProtect" style="color: black" data-ve-attributes="{"style":"color: black"}">3)</span></sup>'''<ref name=":0" />
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	<span class="ve-pasteProtect" style="mso-list:Ignore" data-ve-attributes="{"style":"mso-list:Ignore"}">2.<span class="ve-pasteProtect" style="font:7.0pt "Times New Roman"" data-ve-attributes="{"style":"font:7.0pt \"Times New Roman\""}"> </span></span>Henter JI, Horne A, Arico M, Egeler RM, Filipovich AH,et al. HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatric<span class="ve-pasteProtect" style="letter-spacing:-1.1pt" data-ve-attributes="{"style":"letter-spacing:-1.1pt"}"> </span>blood		<span class="ve-pasteProtect" style="mso-list:Ignore" data-ve-attributes="{"style":"mso-list:Ignore"}">2.<span class="ve-pasteProtect" style="font:7.0pt "Times New Roman"" data-ve-attributes="{"style":"font:7.0pt \"Times New Roman\""}"> </span></span>Henter JI, Horne A, Arico M, Egeler RM, Filipovich AH,et al. HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatric<span class="ve-pasteProtect" style="letter-spacing:-1.1pt" data-ve-attributes="{"style":"letter-spacing:-1.1pt"}"> </span>blood
	<span class="ve-pasteProtect" style="mso-list:Ignore" data-ve-attributes="{"style":"mso-list:Ignore"}">3.<span class="ve-pasteProtect" style="font:7.0pt "Times New Roman"" data-ve-attributes="{"style":"font:7.0pt \"Times New Roman\""}"> </span></span>Lachmann, G., La Rosée, P., Schenk, T. et al. Anaesthesist (2016) 65: 776. <nowiki>https://doi.org/10.1007/s00101-016-0216-x</nowiki><br />		<span class="ve-pasteProtect" style="mso-list:Ignore" data-ve-attributes="{"style":"mso-list:Ignore"}">3.<span class="ve-pasteProtect" style="font:7.0pt "Times New Roman"" data-ve-attributes="{"style":"font:7.0pt \"Times New Roman\""}"> </span></span>Lachmann, G., La Rosée, P., Schenk, T. et al. Anaesthesist (2016) 65: 776. <nowiki>https://doi.org/10.1007/s00101-016-0216-x</nowiki><br />
			<references />

Erkrankung:Antibiotikatherapie bei Sepsis - Revision history

imported>WikiSysop at 06:49, 4 June 2020

imported>WikiSysop at 06:45, 4 June 2020

imported>Bestem: Tabelle und Einzelnachweise

imported>Bestem at 10:44, 9 April 2020

imported>Bestem at 12:07, 3 April 2020

imported>Bestem at 12:04, 3 April 2020

imported>Bestem at 12:03, 3 April 2020

imported>Bestem at 15:18, 2 April 2020

imported>Bestem at 15:16, 2 April 2020

imported>Bestem: Übertragung aus der PDF Datei abgeschlossen. Evtl. noch Schriftgröße anpassen, sonst fertig