imported>Brinkery |
imported>Bestem |
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| == Diagnostik ==
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| {{DGI:Kryptokokkose/Diagnostik/Diagnosekriterien}}
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| {{DGI:Kryptokokkose/Diagnostik/Diagnostische_Schritte}}
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| {{DGI:Kryptokokkose/Diagnostik/Differentialdiagnosen}}
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| === Differentialdiagnosen ===
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| {| class="wikitable sortable bs-exportable MsoTableGrid" border="1" cellspacing="0" cellpadding="0" width="1108" style="border-collapse:collapse;mso-table-layout-alt:fixed;border:none;
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| mso-border-alt:solid windowtext .5pt;mso-yfti-tbllook:1184;mso-padding-alt:
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| 0cm 5.4pt 0cm 5.4pt"
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| |+<span class="toctext"><span style="color: black">Differentialdiagnose der cerebralen Kryptokokkose (Bildgebung und Liqorbefund), modifiziert nach Tan et al.<sup>16</sup></span></span>
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| | style="width:84.8pt;" width="113" valign="top" |<span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;mso-no-proof:yes">'''Differentialdiagnose'''</span></span>
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| | style="width:85.95pt;" width="115" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">'''Verdrängender Effekt'''</span></span></span>
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| | style="width:55.8pt;" width="74" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:
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| 10.5pt;font-family:"Arial",sans-serif;mso-no-proof:yes">'''CD4-Zell zahl (HIV)'''</span></span></span>
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| | style="width:99.25pt;" width="132" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">'''Anteil solitäre Läsionen'''</span> </span></span>
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| | style="width:3.0cm;" width="113" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">'''Lokalisation'''</span></span></span>
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| | style="width:92.15pt;" width="123" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">'''Enhancement im cCT / cMRT'''</span></span></span>
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| | style="width:150.8pt;" width="201" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">'''Sonstige Merkmale<span style="color: #0060DF"> </span>'''</span></span></span>
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| | style="width:177.35pt;" width="236" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">'''Liquorbefund'''</span> </span></span>
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| |- style="height:87.15ptpx;"
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| | style="width:84.8pt;" width="113" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">'''Toxoplasmose'''</span></span></span>
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| | style="width:85.95pt;" width="115" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">häufig</span> </span></span>
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| | style="width:55.8pt;" width="74" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span style="font-size:11.0pt">< 200/µl</span></span>
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| | style="width:99.25pt;" width="132" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">Häufig multiple Läsionen</span> </span></span>
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| | style="width:3.0cm;" width="113" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">frontal, Basal- ganglien, parietal</span> </span></span>
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| | style="width:92.15pt;" width="123" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">häufig ringförmiges Enhancement</span> </span></span>
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| | style="width:150.8pt;" width="201" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">Durchmesser 1-2 cm <span style="mso-spacerun:yes"> </span> Zeit von Symptombeginn bis zur klinischen räsentation:Tage<span style="color: #0060DF"> </span>Eine negative Toxoplasmose-Serologie macht eine cerebrale Toxoplasmose unwahrscheinlich, jedoch kein Auschlusskriterium.<span style="color: #0060DF"> </span></span></span></span>
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| | style="width:177.35pt;" width="236" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">Zellpopulation:</span> <span style="font-size:
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| 10.5pt;font-family:"Arial",sans-serif;mso-no-proof:yes">normal bis lymphozytäre Pleozytose <span style="mso-spacerun:yes"> </span> Glucose: normal bis erniedrigt Protein: normal bis erhöht<span style="mso-spacerun:yes"> </span> Sonstiges: Toxoplasmose PCR aus dem Liquor – Sensitivität 50-80% und Spezifität 100%</span></span></span>
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| |- style="height:143.05ptpx;"
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| | style="width:84.8pt;" width="113" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">'''PML'''</span> </span></span>
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| | style="width:85.95pt;" width="115" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">selten</span> </span></span>
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| | style="width:55.8pt;" width="74" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span style="font-size:11.0pt">< 100/µl, gelegentlich auch höher </span></span>
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| | style="width:99.25pt;" width="132" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">häufig solitär (50%)</span> </span></span>
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| | style="width:3.0cm;" width="113" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">Subcortical weisse Substanz, Cerrebellum, Hirnstamm</span></span></span>
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| | style="width:92.15pt;" width="123" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">ca. 25% mit Enhancement (insbesondere bei IRIS)</span> </span></span>
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| | style="width:150.8pt;" width="201" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="color: black">(T2 Wichtung): Hyperintense Areale in der weissen Substanz (T1-Wichtung): Hypointense Läsionen mit Aussprachung der Kortikalis <span style="mso-spacerun:yes"> </span> </span><span style="font-size:
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| 10.5pt;font-family:"Arial",sans-serif;mso-no-proof:yes">Zeit von Symptombeginn bis zur klinischen Präsentation: Wochen bis Monate, selten akut mit dem Bild eines Apoplex</span></span></span>
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| | style="width:177.35pt;" width="236" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">Zellpopulation:</span> <span style="font-size:
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| 10.5pt;font-family:"Arial",sans-serif;mso-no-proof:yes">normal bis selten lymphozytäre Pleozytose <span style="mso-spacerun:yes"> </span> Glucose: normal <span style="mso-spacerun:yes"> </span> Protein: normal bis erhöht<span style="mso-spacerun:yes"> </span> Sonstiges: JC-PCR aus dem Liquor – Sensitivität 50-90% und Spezifität 90-100%</span></span></span>
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| |- style="height:107.0ptpx;"
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| | style="width:84.8pt;" width="113" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">'''Lymphom'''</span> </span></span>
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| | style="width:85.95pt;" width="115" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">häufig</span> </span></span>
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| | style="width:55.8pt;" width="74" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span style="font-size:11.0pt">< 100/µl</span></span>
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| | style="width:99.25pt;" width="132" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">häufig solitär (50%)</span> </span></span>
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| | style="width:3.0cm;" width="113" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">periventrikulär, frontal, Cerebellum, temporal</span></span></span>
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| | style="width:92.15pt;" width="123" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="color: black">häufig, heterogenes Enhancement</span></span></span>
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| | style="width:150.8pt;" width="201" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="color: black">In der Regel > 3cm Durchmesser <span style="mso-spacerun:yes"> </span> </span><span style="font-size:
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| 10.5pt;font-family:"Arial",sans-serif;mso-no-proof:yes">Zeit von Symptombeginn bis zur klinischen Präsentation: Wochen</span> </span></span>
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| | style="width:177.35pt;" width="236" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">Zellpopulation:</span> <span style="font-size:
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| 10.5pt;font-family:"Arial",sans-serif;mso-no-proof:yes">normal bis lymphozytäre Pleozytose, FACS-Analyse – Nachweis von monoklonalen Lymphozyten <span style="mso-spacerun:yes"> </span> Glucose: normal <span style="mso-spacerun:yes"> </span> Protein: normal bis erhöht<span style="mso-spacerun:yes"> </span> Sonstiges: EBV-PCR aus dem Liquor – Sensitivität 100% und Spezifität 50%.</span> </span></span>
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| |- style="height:23.6ptpx;"
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| | style="width:84.8pt;" width="113" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">'''CMV'''</span> </span></span>
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| | style="width:85.95pt;" width="115" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">nein</span> </span></span>
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| | style="width:55.8pt;" width="74" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span style="font-size:11.0pt">< 50/µl</span></span>
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| | style="width:99.25pt;" width="132" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:
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| 10.5pt;font-family:"Arial",sans-serif;mso-no-proof:yes">-</span></span></span>
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| | style="width:3.0cm;" width="113" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">periventrikulär</span> </span></span>
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| | style="width:92.15pt;" width="123" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="color: black">< 50 % periventrikuläres (meningeales) <span style="mso-spacerun:yes"> </span>Enhancement </span></span></span>
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| | style="width:150.8pt;" width="201" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="color: black">in > 50% der Fälle unauffälliges MRT <span style="mso-spacerun:yes"> </span></span><span style="font-size:
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| 10.5pt;font-family:"Arial",sans-serif;mso-no-proof:yes">Zeit von Symptombeginn bis zur klinischen Präsentation: Tage</span></span></span>
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| | style="width:177.35pt;" width="236" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">Zellpopulation:</span> <span style="font-size:
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| 10.5pt;font-family:"Arial",sans-serif;mso-no-proof:yes">normal, selten erhöhte Neutrophilenzahl <span style="mso-spacerun:yes"> </span> Glucose: normal <span style="mso-spacerun:yes"> </span> Protein: normal bis erhöht<span style="mso-spacerun:yes"> </span> Sonstiges: CMV-PCR aus dem Liquor – Sensitivität > 90% und Spezifität >90%</span></span></span>
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| |- style="height:52.05ptpx;"
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| | style="width:84.8pt;" width="113" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">'''Kryptokokkose'''</span></span></span>
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| | style="width:85.95pt;" width="115" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">kommunizierender Hydrocephalus durch erhöhten intrakranialer Druck</span> </span></span>
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| | style="width:55.8pt;" width="74" valign="top" | <span style="mso-bookmark:_Hlk61588457"><span style="font-size:11.0pt">< 100/µl, (selten < 200/µl)</span></span>
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| | style="width:99.25pt;" width="132" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">häufig multiple Läsionen (Kryptokokkome)</span> </span></span>
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| | style="width:3.0cm;" width="113" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">Basalganglien</span></span></span>
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| | style="width:92.15pt;" width="123" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">Leptomeningeales Enhancement, insbesondere bei IRIS</span> </span></span>
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| | style="width:150.8pt;" width="201" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">häufig „ punched-out” zystische Läsionen<span style="color: #0060DF"> <span style="mso-spacerun:yes"> </span></span>Zeit von Symptombeginn bis zur klinischen Präsentation: Tage</span></span></span>
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| | style="width:177.35pt;" width="236" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">Zellpopulation:</span> <span style="font-size:
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| 10.5pt;font-family:"Arial",sans-serif;mso-no-proof:yes">normal bis lymphozytäre Pleozytose <span style="mso-spacerun:yes"> </span> Glucose: normal bis erniedrigt <span style="mso-spacerun:yes"> </span> Protein: normal bis erhöht</span></span></span>
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| |- style="height:95.2ptpx;"
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| | style="width:84.8pt;" width="113" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">'''HSV'''</span> </span></span>
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| | style="width:85.95pt;" width="115" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">minimal</span> </span></span>
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| | style="width:55.8pt;" width="74" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">variabel</span> </span></span>
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| | style="width:99.25pt;" width="132" valign="top" |<span style="mso-bookmark:
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| _Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:
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| "Arial",sans-serif;mso-no-proof:yes">-</span></span></span>
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| | style="width:3.0cm;" width="113" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">Temporallappen</span></span></span>
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| | style="width:92.15pt;" width="123" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">häufig Enhancement</span> </span></span>
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| | style="width:150.8pt;" width="201" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">Beteiligung des Hirnstamms, Kleinhirn, Diencephalon und der periventrikulären Regionen. <span style="mso-spacerun:yes"> </span>Zeit von Symptombeginn bis zur klinischen Präsentation: Tage</span></span></span>
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| | style="width:177.35pt;" width="236" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">Zellpopulation:</span> <span style="font-size:
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| 10.5pt;font-family:"Arial",sans-serif;mso-no-proof:yes">in der Regel lymphozytäre Pleozytose <span style="mso-spacerun:yes"> </span> Glucose: normal <span style="mso-spacerun:yes"> </span> Protein: normal bis erhöht</span></span></span>
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| |- style="height:99.95ptpx;"
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| | style="width:84.8pt;" width="113" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">'''Tuberkulose'''</span> </span></span>
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| | style="width:85.95pt;" width="115" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">Hydrocephalus möglich</span> </span></span>
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| | style="width:55.8pt;" width="74" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">variabel</span> </span></span>
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| | style="width:99.25pt;" width="132" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">Tuberkulome treten häufig multiple auf</span> </span></span>
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| | style="width:3.0cm;" width="113" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">TB- Meningitis: Infratentoriell mit Basalganglien-/Corticalinfarkten</span></span></span>
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| | style="width:92.15pt;" width="123" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">< 50% basales Enhancement</span> </span></span>
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| | style="width:150.8pt;" width="201" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">Hämorrhagien, Tuberkulome oder Abszesse möglich <span style="mso-spacerun:yes"> </span> Zeit von Symptombeginn bis zur klinischen Präsentation: Tage bis Wochen</span></span></span>
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| <span style="mso-bookmark:_Hlk61588457"></span>
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| | style="width:177.35pt;" width="236" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">Zellpopulation:</span> <span style="font-size:
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| 10.5pt;font-family:"Arial",sans-serif;mso-no-proof:yes">in der Regel lymphozytäre Pleozytose <span style="mso-spacerun:yes"> </span> Glucose: erniedrigt <span style="mso-spacerun:yes"> </span> Protein: normal bis deutlich erhöht <span style="mso-spacerun:yes"> </span> Sonstiges: Laktat erhöht, schwere Schrankenstörung, IGA-Dominanz(Immunglobulinsynthese), häufig auch pulmonale Beteiligung (CT-Thorax)</span> </span></span>
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| |- style="height:67.85ptpx;"
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| | style="width:84.8pt;" width="113" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">'''Hirnabszess'''</span> </span></span>
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| | style="width:85.95pt;" width="115" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">möglich</span> </span></span>
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| | style="width:55.8pt;" width="74" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">variabel</span></span></span>
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| | style="width:99.25pt;" width="132" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">sowohl solitär als auch multiple Läsionen z.B. im Rahmen einer Endokarditis möglich</span></span></span>
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| | style="width:3.0cm;" width="113" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="color: black">supratentoriell, insb. im Frontal- und</span> [https://www.amboss.com/de/wissen/Gro%C3%9Fhirn#Zaad99956bd89838c4d6bbb8efd53379b <span style="color: black">Parietallappen</span>]<span style="color: black">, subkortikal</span></span></span>
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| | style="width:92.15pt;" width="123" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">T1-Sequenz mit KM: ringförmiges Enhancement</span></span></span>
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| <span style="mso-bookmark:_Hlk61588457"></span>
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| | style="width:150.8pt;" width="201" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">DWI-Sequenz: Hyperintenses zentrales Areal <span style="mso-spacerun:yes"> </span> Zeit von Symptombeginn bis zur klinischen Präsentation: Tage</span></span></span>
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| | style="width:177.35pt;" width="236" valign="top" |<span style="mso-bookmark:_Hlk61588457"><span class="toctext"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;
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| mso-no-proof:yes">(bei begleitender Meningitis) Zellpopulation:</span> <span style="font-size:
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| 10.5pt;font-family:"Arial",sans-serif;mso-no-proof:yes">in der Regel granulozytäre Pleozytose <span style="mso-spacerun:yes"> </span> Glucose: erniedrigt <span style="mso-spacerun:yes"> </span> Protein: normal bis deutlich erhöht <span style="mso-spacerun:yes"> </span></span> </span></span>
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| |}
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| <br />
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