DGI:ZNS-Infektionen/Hirnabszess/Klinisches Bild: Difference between revisions

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<br /><span class="ve-pasteProtect" style="box-sizing: inherit; font-family: Arial, sans-serif;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;}"><span class="ve-pasteProtect" style="box-sizing: inherit;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit;&quot;}"></span></span><span class="ve-pasteProtect" style="box-sizing: inherit; font-family: Arial, sans-serif;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;}"><span class="ve-pasteProtect" style="box-sizing: inherit;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit;&quot;}"></span></span><span class="ve-pasteProtect" style="box-sizing: inherit; font-family: Arial, sans-serif;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;}"><span class="ve-pasteProtect" style="box-sizing: inherit;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit;&quot;}"></span></span>
===<span class="ve-pasteProtect" style="box-sizing: inherit; font-family: Arial, sans-serif;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;}">Epidemiologie</span>===
===<span class="ve-pasteProtect" style="box-sizing: inherit; font-family: Arial, sans-serif;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;}">Epidemiologie</span>===
<span class="ve-pasteProtect" style="box-sizing: inherit; font-family: Arial, sans-serif;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;}">Die Inzidenz in Industrieländern wird zwischen 0,3-0,9/100.000 Einwohner:innen geschätzt. Männer sind 2-3 Mal so häufig betroffen, das mittlere Alter beträgt 30-40 Jahre </span><ref>Nau R. Leitlinien für Diagnostik und Therapie in der Neurologie. Hirnabszess. AWMF-Registernummer: 030/108. <nowiki>https://dgn.org/leitlinien/ll-030-108-hirnabszess-2021</nowiki></ref><ref>Alvis Miranda H. et al. Brain abscess: Current management. J Neurosci Rural Pract 2013; 4(Suppl 1): p. S67-81.</ref><ref>Brouwer MC et al. Brain abscess. N Engl J Med 2014; 371(5): p. 447-56.</ref><span class="ve-pasteProtect" style="box-sizing: inherit; font-family: Arial, sans-serif;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;}">.</span><span class="ve-pasteProtect" style="box-sizing: inherit; font-family: Arial, sans-serif;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;}"><span class="ve-pasteProtect" style="box-sizing: inherit;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit;&quot;}"></span></span><span class="ve-pasteProtect" style="box-sizing: inherit; font-family: Arial, sans-serif;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;}"><span class="ve-pasteProtect" style="box-sizing: inherit;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit;&quot;}"></span></span><span class="ve-pasteProtect" style="box-sizing: inherit; font-family: Arial, sans-serif;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;}"><span class="ve-pasteProtect" style="box-sizing: inherit;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit;&quot;}"></span></span><references />
<span class="ve-pasteProtect" style="box-sizing: inherit; font-family: Arial, sans-serif;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;}">Die Inzidenz in Industrieländern wird zwischen 0,3-0,9/100.000 Einwohner:innen geschätzt. Männer sind 2-3 Mal so häufig betroffen, das mittlere Alter beträgt 30-40 Jahre </span><ref>Nau R. Leitlinien für Diagnostik und Therapie in der Neurologie. Hirnabszess. AWMF-Registernummer: 030/108. <nowiki>https://dgn.org/leitlinien/ll-030-108-hirnabszess-2021</nowiki></ref><ref>Alvis Miranda H. et al. Brain abscess: Current management. J Neurosci Rural Pract 2013; 4(Suppl 1): p. S67-81.</ref><ref>Brouwer MC et al. Brain abscess. N Engl J Med 2014; 371(5): p. 447-56.</ref><span class="ve-pasteProtect" style="box-sizing: inherit; font-family: Arial, sans-serif;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;}">.</span><span class="ve-pasteProtect" style="box-sizing: inherit; font-family: Arial, sans-serif;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;}"><span class="ve-pasteProtect" style="box-sizing: inherit;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit;&quot;}"></span></span><span class="ve-pasteProtect" style="box-sizing: inherit; font-family: Arial, sans-serif;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;}"><span class="ve-pasteProtect" style="box-sizing: inherit;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit;&quot;}"></span></span><span class="ve-pasteProtect" style="box-sizing: inherit; font-family: Arial, sans-serif;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit; font-family: Arial, sans-serif;&quot;}"><span class="ve-pasteProtect" style="box-sizing: inherit;" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit;&quot;}"></span></span>

Latest revision as of 19:59, 9 August 2021

Klinische Situationen

Das häufigste Symptom ist der Kopfschmerz (80%), welcher begleitet sein kann von Übelkeit und Erbrechen. Fieber tritt bei bis zu 50% der Patient:innen auf. Fokale oder generalisierte epileptische Anfälle treten in bis zu 25% der Fälle auf. Die weitere Symptomatik hängt von der Lokalisation des Hirnabszesses ab. Eine Vigilanzminderung und/oder neurologische Herdsymptome, wie z.B. Hemiparese, treten in 30-61% der Fälle auf [1][2].

Epidemiologie

Die Inzidenz in Industrieländern wird zwischen 0,3-0,9/100.000 Einwohner:innen geschätzt. Männer sind 2-3 Mal so häufig betroffen, das mittlere Alter beträgt 30-40 Jahre [3][4][5].

  1. Darlow CA et al. Microbial aetiology of brain abscess in a UK cohort: Prominent role of Streptococcus intermedius. J Infect 2020; 80(6): p. 623-629.
  2. Nau R. Leitlinien für Diagnostik und Therapie in der Neurologie. Hirnabszess. AWMF-Registernummer: 030/108. https://dgn.org/leitlinien/ll-030-108-hirnabszess-2021
  3. Nau R. Leitlinien für Diagnostik und Therapie in der Neurologie. Hirnabszess. AWMF-Registernummer: 030/108. https://dgn.org/leitlinien/ll-030-108-hirnabszess-2021
  4. Alvis Miranda H. et al. Brain abscess: Current management. J Neurosci Rural Pract 2013; 4(Suppl 1): p. S67-81.
  5. Brouwer MC et al. Brain abscess. N Engl J Med 2014; 371(5): p. 447-56.