DGI:ZNS-Infektionen/Nosokomiale Ventrikulitis und Meningitis/Diagnostik/Diagnosekriterien: Difference between revisions

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===<span class="mw-headline" id="Diagnosekriterien" style="box-sizing: inherit;">Diagnosekriterien</span>===
 
<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;\nmso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;\nmso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Die Diagnose einer nosokomialen Ventrikulitis bzw. Meningitis ist schwierig</span> <sup id="cite_ref-:0_1-0" class="reference" style="box-sizing: inherit; font-size: 13.2px; line-height: 1; position: relative; vertical-align: baseline; top: -0.5em; unicode-bidi: isolate; white-space: nowrap;">[[DGI:Nosokomiale Ventrikulitis und Meningitis/Diagnostik#cite%20note-%3A0-1|[1]]]</sup><span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\n\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;\nmso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">. Es gibt verschiedene Definitionen, die eine moderate Übereinstimmung aufweisen</span> <sup id="cite_ref-2" class="reference" style="box-sizing: inherit; font-size: 13.2px; line-height: 1; position: relative; vertical-align: baseline; top: -0.5em; unicode-bidi: isolate; white-space: nowrap;">[[DGI:Nosokomiale Ventrikulitis und Meningitis/Diagnostik#cite%20note-2|[2]]]</sup><span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\n\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;\nmso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">. Nachstehend ist die Definition des amerikanischen <span class="mw-lingo-term" data-lingo-term-id="b451ae487bde3a3338f110920744afa8" data-hasqtip="0" style="box-sizing: inherit; border-bottom: 1px dotted rgb(187, 187, 255); cursor: default;">CDC</span> (Center for Disease Control and Prevention) aufgeführt, die auch in der Leitlinie der <span class="mw-lingo-term" data-lingo-term-id="e9acc92236c36432570f50b0a2700617" data-hasqtip="1" style="box-sizing: inherit; border-bottom: 1px dotted rgb(187, 187, 255); cursor: default;">IDSA</span> (Infectious Diseases Society of America) verwendet wird</span> <sup id="cite_ref-:0_1-1" class="reference" style="box-sizing: inherit; font-size: 13.2px; line-height: 1; position: relative; vertical-align: baseline; top: -0.5em; unicode-bidi: isolate; white-space: nowrap;">[[DGI:Nosokomiale Ventrikulitis und Meningitis/Diagnostik#cite%20note-%3A0-1|[1]]]</sup><span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\n\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;\nmso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">.</span><span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;\nmso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;\nmso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Die Diagnose wird gesichert durch eines der folgenden Kriterien</span>
<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;\nmso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;\nmso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Die Diagnose einer nosokomialen Ventrikulitis bzw. Meningitis ist schwierig</span> <ref name=":a0"> Tunkel AR, Hasbun R, Bhimraj A, Byers K, Kaplan SL, Michael Scheld W, van de Beek D, Bleck TP, Garton HJ, Zunt JR: 2017 Infectious Diseases Society of America's Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis. Clin Infect Dis 2017; 64: e34–e65</ref><span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\n\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;\nmso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">. Es gibt verschiedene Definitionen, die eine moderate Übereinstimmung aufweisen</span><ref>Reyes MM, Munigala S, Church EL, Kulik TB, Keyrouz SG, Zipfel GJ, Warren DK: Comparing External Ventricular Drains-Related Ventriculitis Surveillance Definitions. Infect Control Hosp Epidemiol 2017; 38(5):574-579</ref><span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\n\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;\nmso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">. Nachstehend ist die Definition des amerikanischen <span class="mw-lingo-term" data-lingo-term-id="b451ae487bde3a3338f110920744afa8" data-hasqtip="0" style="box-sizing: inherit; border-bottom: 1px dotted rgb(187, 187, 255); cursor: default;">CDC</span> (Center for Disease Control and Prevention) aufgeführt, die auch in der Leitlinie der <span class="mw-lingo-term" data-lingo-term-id="e9acc92236c36432570f50b0a2700617" data-hasqtip="1" style="box-sizing: inherit; border-bottom: 1px dotted rgb(187, 187, 255); cursor: default;">IDSA</span> (Infectious Diseases Society of America) verwendet wird</span><ref name=":a0" /><span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\n\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;\nmso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">.</span><span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;\nmso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;\nmso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Die Diagnose wird gesichert durch eines der folgenden Kriterien</span>


*<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\n\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;\nmso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Kultureller Nachweis von Erregern aus dem Liquor</span>
*<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\n\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;\nmso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Kultureller Nachweis von Erregern aus dem Liquor</span>
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**<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:\nCalibri;mso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Nachweis von Erregern im Blut</span>
**<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:\nCalibri;mso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Nachweis von Erregern im Blut</span>
**<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:\nCalibri;mso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Positiver IgM-Antikörpertiter oder vierfacher IgG-Titeranstieg für Erreger in wiederholt entnommenen Serumproben</span>
**<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:\nCalibri;mso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Positiver IgM-Antikörpertiter oder vierfacher IgG-Titeranstieg für Erreger in wiederholt entnommenen Serumproben</span>
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# <span class="mw-cite-backlink" style="box-sizing: inherit; user-select: none;">↑ <sup style="box-sizing: inherit; font-size: 13.2px; line-height: 1; position: relative; vertical-align: baseline; top: -0.5em;">[[DGI:Nosokomiale Ventrikulitis und Meningitis/Diagnostik#cite%20ref-%3A0%201-0|<span class="cite-accessibility-label" style="box-sizing: inherit; user-select: none; top: -99999px; clip: rect(1px, 1px, 1px, 1px); overflow: hidden; position: absolute !important; padding: 0px !important; border: 0px !important; height: 1px !important; width: 1px !important;">Hochspringen nach:</span>1,0]][[DGI:Nosokomiale Ventrikulitis und Meningitis/Diagnostik#cite%20ref-%3A0%201-1|1,1]]</sup></span> <span class="reference-text" style="box-sizing: inherit;"><span style="color: rgb(51, 51, 51)">28. <span class="ve-pasteprotect" style="box-sizing: inherit;"><span data-ve-attributes="{&quot;style&quot;:&quot;mso-tab-count:1&quot;}" style="box-sizing: inherit;">          <span style="box-sizing: inherit;"> </span></span></span>Tunkel AR, Hasbun R, Bhimraj A, Byers K, Kaplan SL, Michael Scheld W, van de Beek D, Bleck TP, Garton HJ, Zunt JR: 2017 Infectious Diseases Society of America's Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis. Clin Infect Dis 2017; 64: e34–e65</span></span>
# <span class="mw-cite-backlink" style="box-sizing: inherit; user-select: none;">[[DGI:Nosokomiale Ventrikulitis und Meningitis/Diagnostik#cite%20ref-2|<span class="cite-accessibility-label" style="box-sizing: inherit; user-select: none; top: -99999px; clip: rect(1px, 1px, 1px, 1px); overflow: hidden; position: absolute !important; padding: 0px !important; border: 0px !important; height: 1px !important; width: 1px !important;">Hochspringen</span>↑]]</span> <span class="reference-text" style="box-sizing: inherit;"><span style="color: rgb(51, 51, 51)">29. <span class="ve-pasteprotect" style="box-sizing: inherit;"><span data-ve-attributes="{&quot;style&quot;:&quot;mso-tab-count:1&quot;}" style="box-sizing: inherit;">          <span style="box-sizing: inherit;"> </span></span></span>Reyes MM, Munigala S, Church EL, Kulik TB, Keyrouz SG, Zipfel GJ, Warren DK: Comparing External Ventricular Drains-Related Ventriculitis Surveillance Definitions. Infect Control Hosp Epidemiol 2017; 38(5):574-579</span></span>
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Latest revision as of 08:34, 14 September 2021

Die Diagnose einer nosokomialen Ventrikulitis bzw. Meningitis ist schwierig [1]. Es gibt verschiedene Definitionen, die eine moderate Übereinstimmung aufweisen[2]. Nachstehend ist die Definition des amerikanischen CDC (Center for Disease Control and Prevention) aufgeführt, die auch in der Leitlinie der IDSA (Infectious Diseases Society of America) verwendet wird[1].Die Diagnose wird gesichert durch eines der folgenden Kriterien

  • Kultureller Nachweis von Erregern aus dem Liquor

ODER

  •    Zwei der folgenden Kriterien:
    • Fieber > 38,0°C oder Kopfschmerzen
    • Meningismus
    • Hirnnervensymptome
  • Und eins der folgenden Kriterien:
    • Erhöhte Leukozytenzahl, erhöhter Proteingehalt und/oder erniedrigter Glucosegehalt im Liquor
    • Mikroskopischer Nachweis von Erregern im Liquor
    • Nachweis von Erregern im Blut
    • Positiver IgM-Antikörpertiter oder vierfacher IgG-Titeranstieg für Erreger in wiederholt entnommenen Serumproben
  1. 1.0 1.1  Tunkel AR, Hasbun R, Bhimraj A, Byers K, Kaplan SL, Michael Scheld W, van de Beek D, Bleck TP, Garton HJ, Zunt JR: 2017 Infectious Diseases Society of America's Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis. Clin Infect Dis 2017; 64: e34–e65
  2. Reyes MM, Munigala S, Church EL, Kulik TB, Keyrouz SG, Zipfel GJ, Warren DK: Comparing External Ventricular Drains-Related Ventriculitis Surveillance Definitions. Infect Control Hosp Epidemiol 2017; 38(5):574-579