DGI:ZNS-Infektionen/Nosokomiale Ventrikulitis und Meningitis/Diagnostik/Diagnosekriterien: Difference between revisions

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=== <span class="mw-headline" id="Diagnosekriterien" style="box-sizing: inherit;">Diagnosekriterien</span> ===
===<span class="mw-headline" id="Diagnosekriterien" style="box-sizing: inherit;">Diagnosekriterien</span>===
<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;\nmso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;\nmso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Die Diagnose einer nosokomialen Ventrikulitis bzw. Meningitis ist schwierig</span> <sup id="cite_ref-:0_1-0" class="reference" style="box-sizing: inherit; font-size: 13.2px; line-height: 1; position: relative; vertical-align: baseline; top: -0.5em; unicode-bidi: isolate; white-space: nowrap;">[[DGI:Nosokomiale Ventrikulitis und Meningitis/Diagnostik#cite%20note-%3A0-1|[1]]]</sup><span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\n\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;\nmso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">. Es gibt verschiedene Definitionen, die eine moderate Übereinstimmung aufweisen</span> <sup id="cite_ref-2" class="reference" style="box-sizing: inherit; font-size: 13.2px; line-height: 1; position: relative; vertical-align: baseline; top: -0.5em; unicode-bidi: isolate; white-space: nowrap;">[[DGI:Nosokomiale Ventrikulitis und Meningitis/Diagnostik#cite%20note-2|[2]]]</sup><span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\n\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;\nmso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">. Nachstehend ist die Definition des amerikanischen <span class="mw-lingo-term" data-lingo-term-id="b451ae487bde3a3338f110920744afa8" data-hasqtip="0" style="box-sizing: inherit; border-bottom: 1px dotted rgb(187, 187, 255); cursor: default;">CDC</span> (Center for Disease Control and Prevention) aufgeführt, die auch in der Leitlinie der <span class="mw-lingo-term" data-lingo-term-id="e9acc92236c36432570f50b0a2700617" data-hasqtip="1" style="box-sizing: inherit; border-bottom: 1px dotted rgb(187, 187, 255); cursor: default;">IDSA</span> (Infectious Diseases Society of America) verwendet wird</span> <sup id="cite_ref-:0_1-1" class="reference" style="box-sizing: inherit; font-size: 13.2px; line-height: 1; position: relative; vertical-align: baseline; top: -0.5em; unicode-bidi: isolate; white-space: nowrap;">[[DGI:Nosokomiale Ventrikulitis und Meningitis/Diagnostik#cite%20note-%3A0-1|[1]]]</sup><span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\n\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;\nmso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">.</span><span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;\nmso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;\nmso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Die Diagnose wird gesichert durch eines der folgenden Kriterien</span>
<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;\nmso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;\nmso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Die Diagnose einer nosokomialen Ventrikulitis bzw. Meningitis ist schwierig</span> <sup id="cite_ref-:0_1-0" class="reference" style="box-sizing: inherit; font-size: 13.2px; line-height: 1; position: relative; vertical-align: baseline; top: -0.5em; unicode-bidi: isolate; white-space: nowrap;">[[DGI:Nosokomiale Ventrikulitis und Meningitis/Diagnostik#cite%20note-%3A0-1|[1]]]</sup><span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\n\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;\nmso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">. Es gibt verschiedene Definitionen, die eine moderate Übereinstimmung aufweisen</span> <sup id="cite_ref-2" class="reference" style="box-sizing: inherit; font-size: 13.2px; line-height: 1; position: relative; vertical-align: baseline; top: -0.5em; unicode-bidi: isolate; white-space: nowrap;">[[DGI:Nosokomiale Ventrikulitis und Meningitis/Diagnostik#cite%20note-2|[2]]]</sup><span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\n\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;\nmso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">. Nachstehend ist die Definition des amerikanischen <span class="mw-lingo-term" data-lingo-term-id="b451ae487bde3a3338f110920744afa8" data-hasqtip="0" style="box-sizing: inherit; border-bottom: 1px dotted rgb(187, 187, 255); cursor: default;">CDC</span> (Center for Disease Control and Prevention) aufgeführt, die auch in der Leitlinie der <span class="mw-lingo-term" data-lingo-term-id="e9acc92236c36432570f50b0a2700617" data-hasqtip="1" style="box-sizing: inherit; border-bottom: 1px dotted rgb(187, 187, 255); cursor: default;">IDSA</span> (Infectious Diseases Society of America) verwendet wird</span> <sup id="cite_ref-:0_1-1" class="reference" style="box-sizing: inherit; font-size: 13.2px; line-height: 1; position: relative; vertical-align: baseline; top: -0.5em; unicode-bidi: isolate; white-space: nowrap;">[[DGI:Nosokomiale Ventrikulitis und Meningitis/Diagnostik#cite%20note-%3A0-1|[1]]]</sup><span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\n\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;\nmso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">.</span><span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;\nmso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;\nmso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Die Diagnose wird gesichert durch eines der folgenden Kriterien</span>


* <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\n\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;\nmso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Kultureller Nachweis von Erregern aus dem Liquor</span>
*<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\n\&quot;Times New Roman\&quot;;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;\nmso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Kultureller Nachweis von Erregern aus dem Liquor</span>


ODER
ODER


* <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;mso-list:Ignore&quot;}" style="box-sizing: inherit;"><span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font:7.0pt \&quot;Times New Roman\&quot;&quot;}" style="box-sizing: inherit; font: 7pt &quot;Times New Roman&quot;;">   </span></span>Zwei der folgenden Kriterien:
*<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;mso-list:Ignore&quot;}" style="box-sizing: inherit;"><span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font:7.0pt \&quot;Times New Roman\&quot;&quot;}" style="box-sizing: inherit; font: 7pt &quot;Times New Roman&quot;;">   </span></span>Zwei der folgenden Kriterien:
** Fieber > 38,0°C oder Kopfschmerzen
**Fieber > 38,0°C oder Kopfschmerzen
** Meningismus
**Meningismus
** Hirnnervensymptome
**Hirnnervensymptome


* Und eins der folgenden Kriterien:
*Und eins der folgenden Kriterien:
** <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:\nCalibri;mso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Erhöhte Leukozytenzahl, erhöhter Proteingehalt und/oder erniedrigter Glucosegehalt im Liquor</span>
**<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:\nCalibri;mso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Erhöhte Leukozytenzahl, erhöhter Proteingehalt und/oder erniedrigter Glucosegehalt im Liquor</span>
** <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:\nCalibri;mso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Mikroskopischer Nachweis von Erregern im Liquor</span>
**<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:\nCalibri;mso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Mikroskopischer Nachweis von Erregern im Liquor</span>
** <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:\nCalibri;mso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Nachweis von Erregern im Blut</span>
**<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:\nCalibri;mso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Nachweis von Erregern im Blut</span>
** <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:\nCalibri;mso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Positiver IgM-Antikörpertiter oder vierfacher IgG-Titeranstieg für Erreger in wiederholt entnommenen Serumproben</span>
**<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;font-size:12.0pt;mso-fareast-font-family:\&quot;Times New Roman\&quot;;mso-bidi-font-family:\nCalibri;mso-bidi-theme-font:minor-latin;mso-ansi-language:DE&quot;}" style="box-sizing: inherit; font-size: 12pt;">Positiver IgM-Antikörpertiter oder vierfacher IgG-Titeranstieg für Erreger in wiederholt entnommenen Serumproben</span>
 
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*
 
# <span class="mw-cite-backlink" style="box-sizing: inherit; user-select: none;">↑ <sup style="box-sizing: inherit; font-size: 13.2px; line-height: 1; position: relative; vertical-align: baseline; top: -0.5em;">[[DGI:Nosokomiale Ventrikulitis und Meningitis/Diagnostik#cite%20ref-%3A0%201-0|<span class="cite-accessibility-label" style="box-sizing: inherit; user-select: none; top: -99999px; clip: rect(1px, 1px, 1px, 1px); overflow: hidden; position: absolute !important; padding: 0px !important; border: 0px !important; height: 1px !important; width: 1px !important;">Hochspringen nach:</span>1,0]][[DGI:Nosokomiale Ventrikulitis und Meningitis/Diagnostik#cite%20ref-%3A0%201-1|1,1]]</sup></span> <span class="reference-text" style="box-sizing: inherit;"><span style="color: rgb(51, 51, 51)">28. <span class="ve-pasteprotect" style="box-sizing: inherit;"><span data-ve-attributes="{&quot;style&quot;:&quot;mso-tab-count:1&quot;}" style="box-sizing: inherit;">          <span style="box-sizing: inherit;"> </span></span></span>Tunkel AR, Hasbun R, Bhimraj A, Byers K, Kaplan SL, Michael Scheld W, van de Beek D, Bleck TP, Garton HJ, Zunt JR: 2017 Infectious Diseases Society of America's Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis. Clin Infect Dis 2017; 64: e34–e65</span></span>
# <span class="mw-cite-backlink" style="box-sizing: inherit; user-select: none;">[[DGI:Nosokomiale Ventrikulitis und Meningitis/Diagnostik#cite%20ref-2|<span class="cite-accessibility-label" style="box-sizing: inherit; user-select: none; top: -99999px; clip: rect(1px, 1px, 1px, 1px); overflow: hidden; position: absolute !important; padding: 0px !important; border: 0px !important; height: 1px !important; width: 1px !important;">Hochspringen</span>↑]]</span> <span class="reference-text" style="box-sizing: inherit;"><span style="color: rgb(51, 51, 51)">29. <span class="ve-pasteprotect" style="box-sizing: inherit;"><span data-ve-attributes="{&quot;style&quot;:&quot;mso-tab-count:1&quot;}" style="box-sizing: inherit;">          <span style="box-sizing: inherit;"> </span></span></span>Reyes MM, Munigala S, Church EL, Kulik TB, Keyrouz SG, Zipfel GJ, Warren DK: Comparing External Ventricular Drains-Related Ventriculitis Surveillance Definitions. Infect Control Hosp Epidemiol 2017; 38(5):574-579</span></span>
 
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Revision as of 09:04, 31 July 2021

Diagnosekriterien

Die Diagnose einer nosokomialen Ventrikulitis bzw. Meningitis ist schwierig [1]. Es gibt verschiedene Definitionen, die eine moderate Übereinstimmung aufweisen [2]. Nachstehend ist die Definition des amerikanischen CDC (Center for Disease Control and Prevention) aufgeführt, die auch in der Leitlinie der IDSA (Infectious Diseases Society of America) verwendet wird [1].Die Diagnose wird gesichert durch eines der folgenden Kriterien

  • Kultureller Nachweis von Erregern aus dem Liquor

ODER

  •    Zwei der folgenden Kriterien:
    • Fieber > 38,0°C oder Kopfschmerzen
    • Meningismus
    • Hirnnervensymptome
  • Und eins der folgenden Kriterien:
    • Erhöhte Leukozytenzahl, erhöhter Proteingehalt und/oder erniedrigter Glucosegehalt im Liquor
    • Mikroskopischer Nachweis von Erregern im Liquor
    • Nachweis von Erregern im Blut
    • Positiver IgM-Antikörpertiter oder vierfacher IgG-Titeranstieg für Erreger in wiederholt entnommenen Serumproben


  1. Hochspringen nach:1,01,1 28.            Tunkel AR, Hasbun R, Bhimraj A, Byers K, Kaplan SL, Michael Scheld W, van de Beek D, Bleck TP, Garton HJ, Zunt JR: 2017 Infectious Diseases Society of America's Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis. Clin Infect Dis 2017; 64: e34–e65
  2. Hochspringen 29.            Reyes MM, Munigala S, Church EL, Kulik TB, Keyrouz SG, Zipfel GJ, Warren DK: Comparing External Ventricular Drains-Related Ventriculitis Surveillance Definitions. Infect Control Hosp Epidemiol 2017; 38(5):574-579